Isle of Palms, South Carolina Vacation Rentals

Explore 815 rental homes and villas in Isle of Palms, South Carolina for your next vacation or business travel. With private vacation home rentals, enjoy a more personalized stay and a wide range of amenities such as Air Condition Homes, Best Affordable Homes and Great for Groups. With a wide range of homes to offer, pricing can start as low as $66 per night with homes containing as many as 12 bedrooms and 11 bathrooms. However you're looking to experience your stay, Homes and Villas by Marriott has your next vacation home waiting.

Types of vacation rentals in Isle of Palms

Where to stay in Isle of Palms

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