Seneca, South Carolina Vacation Rentals

Explore 147 rental homes and villas in Seneca, South Carolina for your next vacation or business travel. With private vacation home rentals, enjoy a more personalized stay and a wide range of amenities such as Air Condition Homes, Best Affordable Homes and Great for Groups. With a wide range of homes to offer, pricing can start as low as $85 per night with homes containing as many as 8 bedrooms and 7 bathrooms. However you're looking to experience your stay, Homes and Villas by Marriott has your next vacation home waiting.

Types of vacation rentals in Seneca

Where to stay in Seneca

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