Homes & Villas by Marriott Bonvoy

Big Pine Key, Florida Vacation Rentals

Explore 391 rental homes and villas in Big Pine Key, Florida for your next vacation or business travel. With private vacation home rentals, enjoy a more personalized stay and a wide range of amenities such as Homes with Pools, Air Condition Homes and Best Affordable Homes. With a wide range of homes to offer, pricing can start as low as $61 per night with homes containing as many as 12 bedrooms and 9 bathrooms. However you're looking to experience your stay, Homes and Villas by Marriott has your next vacation home waiting.

Types of vacation rentals in Big Pine Key

Room for family and space for yourself
Homes

Room for family and space for yourself

Country homes with spectacular views
Villas

Country homes with spectacular views

Prime locations for every lifestyle
Apartments

Prime locations for every lifestyle

Where to stay in Big Pine Key

  • The Frontier Suite
    The Frontier Suite

    Key West, FL

    2 Bedrooms • 6 Guests
    from$216night
  • Coconut Cottage
    Coconut Cottage

    Key West, FL

    1 Bedroom • 4 Guests
    from$259night
  • Primary bedroom features a queen bed.
    Serenity | Guest House in Old Town w/ Shared Pool | Month Long Stays Only

    Key West, FL

    1 Bedroom • 2 Guests
    from$187night
  • Indoor dining area.
    La Casita | Steps to Duval Street in Key West! | Month Long Stays Only

    Key West, FL

    2 Bedrooms • 4 Guests
    from$167night
  • Bottoms Up
    Bottoms Up

    Key West, FL

    1 Bedroom • 2 Guests
    from$92night
  • Shared Pool With String Lights
    Premium Pool View Residence with Private Balcony

    Key West, Florida

    3 Bedrooms • 8 Guests
    from$525night
  • Bathtub
    Top Floor Pool View Suite with Rooftop Balcony

    Key West, Florida

    1 Bedroom • 4 Guests
    from$249night
  • Expansive Island View Residence
    Expansive Island View Residence

    Key West, Florida

    2 Bedrooms • 6 Guests
    from$370night
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